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European Academy of Neurology Guideline on the Management of ALS

Van Damme P, Al-Chalabi A, Andersen PM, et al. European Journal of Neurology. 2024;31(6):e16264. DOI: 10.1111/ene.16264.

Key findings used in wiki

  • This open-access guideline used GRADE methods and addresses multidisciplinary care, communication, nutrition, respiratory support, psychological support, symptom management, and end-of-life care.
  • Coordinated ALS-specialist care should regularly review mobility and daily function, swallowing and nutrition, speech and communication, cough and respiratory function, social-care needs, end-of-life needs, and support needs of family members and caregivers.
  • Speech-language assessment, appropriate augmentative and alternative communication, ongoing review, and training for the person and family/caregivers should not be delayed.
  • The guideline also addresses safe manual handling, caregiver willingness and capacity, respite and emotional support, and earlier advance-care discussions when communication or decision-making may worsen.
  • GiveCare uses these findings as caregiver orientation and questions for the ALS team, not as treatment instructions or clinical thresholds.